stress-activated MAPK cascade 26.231788 stress-activated protein kinase signaling cascade 26.231788 toll-like receptor 1 signaling pathway 25.182498 toll-like receptor 2 signaling pathway 25.182498 MyD88-dependent toll-like receptor signaling pathway 24.327257 TRIF-dependent toll-like receptor signaling pathway 23.299987 Toll signaling pathway 23.299987 toll-like receptor 3 signaling pathway 23.299987 MyD88-independent toll-like receptor signaling pathway 21.501119 toll-like receptor 4 signaling pathway 21.501119 pattern recognition receptor signaling pathway 20.829211 toll-like receptor signaling pathway 20.829211 nitrogen compound metabolic process 19.789323 nucleic acid metabolic process 19.287979 cellular response to stress 18.676845 MAPK cascade 18.026288 positive regulation of defense response 17.998078 activation of innate immune response 17.818597 innate immune response-activating signal transduction 17.818597 nucleobase-containing compound metabolic process 17.575097 cellular nitrogen compound metabolic process 17.310320 positive regulation of innate immune response 16.872882 cellular macromolecule metabolic process 16.294072 regulation of I-kappaB kinase/NF-kappaB cascade 16.068546 macromolecule metabolic process 15.810532 intracellular protein kinase cascade 15.764769 cellular metabolic process 13.937974 JNK cascade 13.464634 death 13.358625 cell death 13.250681 nucleotide-binding oligomerization domain containing signaling pathway 13.213936 regulation of MAP kinase activity 13.131095 positive regulation of apoptotic process 13.124200 positive regulation of cell death 13.124200 positive regulation of programmed cell death 13.124200 activation of MAPK activity 12.291019 apoptotic process 12.247426 regulation of intracellular protein kinase cascade 12.227571 regulation of innate immune response 12.061671 programmed cell death 11.990299 DNA damage checkpoint 11.834949 DNA integrity checkpoint 11.834949 response to DNA damage stimulus 11.767904 metabolic process 11.490713 primary metabolic process 11.458701 mitotic cell cycle G1/S transition DNA damage checkpoint 11.404129 induction of apoptosis by extracellular signals 11.251031 induction of apoptosis 11.103002 induction of programmed cell death 11.103002 regulation of cell cycle arrest 11.102520 G1/S transition of mitotic cell cycle 10.873214 positive regulation of MAP kinase activity 10.816710 regulation of G1/S transition of mitotic cell cycle 10.698837 positive regulation of cell cycle arrest 10.591389 regulation of cellular protein metabolic process 10.506674 regulation of signal transduction 10.456239 nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway 10.450065 cytoplasmic pattern recognition receptor signaling pathway 10.409629 regulation of protein serine/threonine kinase activity 10.142937 regulation of ERBB signaling pathway 10.052253 regulation of epidermal growth factor receptor signaling pathway 10.052253 response to growth factor stimulus 10.022613 regulation of apoptotic process 9.968025 positive regulation of protein serine/threonine kinase activity 9.760371 regulation of programmed cell death 9.754140 regulation of response to stress 9.677574 regulation of protein metabolic process 9.536862 G1/S transition checkpoint 9.459590 mitotic cell cycle G1/S transition checkpoint 9.459590 regulation of protein modification process 9.408071 regulation of cell death 9.391121 activation of protein kinase activity 9.290883 regulation of signaling 9.194612 cellular response to abiotic stimulus 9.128846 regulation of cell cycle process 9.042218 DNA repair 9.027438 signal transduction in response to DNA damage 8.882638 response to mechanical stimulus 8.869061 G1 phase 8.789544 G1 phase of mitotic cell cycle 8.789544 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest 8.761513 signal transduction involved in DNA integrity checkpoint 8.761513 signal transduction involved in G1/S transition checkpoint 8.761513 signal transduction involved in cell cycle checkpoint 8.761513 signal transduction involved in mitotic cell cycle G1/S checkpoint 8.761513 signal transduction involved in mitotic cell cycle G1/S transition DNA damage checkpoint 8.761513 signal transduction involved in mitotic cell cycle checkpoint 8.761513 signal transduction involved in DNA damage checkpoint 8.761513 mitotic cell cycle checkpoint 8.753277 positive regulation of I-kappaB kinase/NF-kappaB cascade 8.638655 cellular response to external stimulus 8.595903 positive regulation of protein phosphorylation 8.562125 DNA metabolic process 8.484280 regulation of protein kinase activity 8.474831 negative regulation of ERBB signaling pathway 8.400652 negative regulation of epidermal growth factor receptor signaling pathway 8.400652 cell cycle checkpoint 8.393364 regulation of protein phosphorylation 8.367933 interphase 8.259033 interphase of mitotic cell cycle 8.259033 positive regulation of protein metabolic process 8.135011 DNA damage response, signal transduction by p53 class mediator 8.017553 signal transduction by p53 class mediator 8.017553 positive regulation of phosphorylation 7.999850 nerve growth factor receptor signaling pathway 7.960592 regulation of kinase activity 7.891567 cellular response to growth factor stimulus 7.872971 regulation of interphase of mitotic cell cycle 7.784186 positive regulation of phosphate metabolic process 7.744341 positive regulation of phosphorus metabolic process 7.744341 negative regulation of molecular function 7.675053 positive regulation of protein kinase activity 7.560527 regulation of phosphorylation 7.494872 intracellular signal transduction 7.383846 positive regulation of cellular protein metabolic process 7.277295 positive regulation of kinase activity 7.237776 response to reactive oxygen species 7.207876 cellular response to chemical stimulus 7.094898 regulation of cell cycle 7.058852 regulation of defense response 7.036753 positive regulation of NF-kappaB transcription factor activity 6.984288 regulation of type I interferon production 6.942320 positive regulation of signal transduction 6.925480 enzyme linked receptor protein signaling pathway 6.791829 positive regulation of transferase activity 6.746208 M/G1 transition of mitotic cell cycle 6.711963 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process 6.711963 negative regulation of ligase activity 6.711963 negative regulation of ubiquitin-protein ligase activity 6.711963 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 6.711963 positive regulation of ligase activity 6.711963 positive regulation of ubiquitin-protein ligase activity 6.711963 positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 6.711963 regulation of ligase activity 6.711963 regulation of ubiquitin-protein ligase activity 6.711963 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 6.711963 regulation of cytokine production 6.678527 positive regulation of cellular process 6.625718 response to abiotic stimulus 6.589617 negative regulation of protein metabolic process 6.543499 regulation of phosphate metabolic process 6.445447 regulation of phosphorus metabolic process 6.445447 I-kappaB kinase/NF-kappaB cascade 6.303282 regulation of transferase activity 6.268328 positive regulation of protein modification process 6.265238 response to oxidative stress 6.139371 positive regulation of cell communication 6.122419 positive regulation of response to stimulus 6.071931 positive regulation of signaling 6.026979 response to chemical stimulus 5.952440 regulation of catalytic activity 5.929738 negative regulation of cellular process 5.928029 cellular response to fibroblast growth factor stimulus 5.897250 response to fibroblast growth factor stimulus 5.897250 positive regulation of molecular function 5.854520 DNA damage response, signal transduction resulting in induction of apoptosis 5.836544 negative regulation of protein modification process 5.796400 regulation of cell communication 5.795163 positive regulation of protein complex assembly 5.694697 induction of apoptosis by intracellular signals 5.618341 S phase 5.606531 S phase of mitotic cell cycle 5.606531 mRNA metabolic process 5.588945 negative regulation of macromolecule metabolic process 5.586199 Notch signaling pathway 5.562704 positive regulation of catalytic activity 5.455865 immune response-activating signal transduction 5.436188 negative regulation of apoptotic process 5.415131 negative regulation of programmed cell death 5.397069 fibroblast growth factor receptor signaling pathway 5.372517 anti-apoptosis 5.344545 Notch receptor processing 5.296249 negative regulation of biological process 5.239321 positive regulation of biological process 5.177014 negative regulation of metabolic process 5.163157 regulation of molecular function 4.995312 activation of immune response 4.991380 viral infectious cycle 4.908533 negative regulation of cellular metabolic process 4.896558 RNA metabolic process 4.875341 negative regulation of catalytic activity 4.866931 regulation of mitotic cell cycle 4.847973 positive regulation of neuron apoptotic process 4.845839 positive regulation of neuron death 4.845839 negative regulation of cell death 4.839721 response to decreased oxygen levels 4.796905 response to hypoxia 4.796905 protein phosphorylation 4.760032 response to oxygen levels 4.756895 response to gamma radiation 4.729545 negative regulation of protein ubiquitination 4.717328 negative regulation of cellular protein metabolic process 4.639793 positive regulation of cell cycle process 4.626509 nucleotide-excision repair 4.591097 transmembrane receptor protein tyrosine kinase signaling pathway 4.589240 regulation of stress-activated MAPK cascade 4.586333 regulation of stress-activated protein kinase signaling cascade 4.586333 negative regulation of signal transduction 4.428807 positive regulation of protein ubiquitination 4.408839 negative regulation of type I interferon production 4.380798 positive regulation of macromolecule metabolic process 4.343950 response to exogenous dsRNA 4.338711 response to hydrogen peroxide 4.337470 regulation of JUN kinase activity 4.313716 response to X-ray 4.313716 ERBB signaling pathway 4.307837 epidermal growth factor receptor signaling pathway 4.307837 immune response-regulating signaling pathway 4.270617 negative regulation of intracellular protein kinase cascade 4.256425 cellular process 4.239308 cellular response to tumor necrosis factor 4.187403 negative regulation of cell communication 4.186406 negative regulation of signaling 4.186406 negative regulation of cytokine production 4.121260 cellular response to stimulus 4.103594 positive regulation of smooth muscle cell proliferation 4.038643 viral genome expression 4.020918 viral transcription 4.020918 mitotic cell cycle 3.989662 response to inorganic substance 3.978384 regulation of fibroblast proliferation 3.961073 regulation of MAPK cascade 3.923919 positive regulation of cellular metabolic process 3.906111 cellular response to interleukin-1 3.891063 positive regulation of immune response 3.815287 response to endogenous stimulus 3.805249 neuron apoptotic process 3.796195 neuron death 3.796195 response to progesterone stimulus 3.788814 cellular response to oxygen levels 3.787462 nuclear-transcribed mRNA catabolic process 3.733511 cellular response to endogenous stimulus 3.683493 macromolecular complex subunit organization 3.670218 positive regulation of intracellular protein kinase cascade 3.661454 phosphorylation 3.637183 cellular response to mechanical stimulus 3.613870 blastocyst development 3.599772 regulation of JNK cascade 3.520422 mammary gland development 3.500413 regulation of myeloid cell differentiation 3.467510 response to UV 3.458816 positive regulation of metabolic process 3.452969 regulation of cellular response to stress 3.346105 cell cycle process 3.340968 nucleosome organization 3.339920 DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis 3.302870 signal transduction by p53 class mediator resulting in induction of apoptosis 3.302870 inflammatory response 3.290781 cellular response to starvation 3.217345 regulation of monooxygenase activity 3.200507 response to glucocorticoid stimulus 3.128285 response to bacterium 3.087118 lipopolysaccharide-mediated signaling pathway 3.076282 protein import 3.064251 response to starvation 3.028229 positive regulation of sequence-specific DNA binding transcription factor activity 3.027195