Notch receptor processing 8.322728 negative regulation of ERBB signaling pathway 6.456195 negative regulation of epidermal growth factor receptor signaling pathway 6.456195 regulation of ERBB signaling pathway 6.028751 regulation of epidermal growth factor receptor signaling pathway 6.028751 I-kappaB kinase/NF-kappaB cascade 5.794894 induction of apoptosis by extracellular signals 5.794112 M/G1 transition of mitotic cell cycle 5.732209 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process 5.732209 negative regulation of ligase activity 5.732209 negative regulation of ubiquitin-protein ligase activity 5.732209 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 5.732209 positive regulation of ligase activity 5.732209 positive regulation of ubiquitin-protein ligase activity 5.732209 positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 5.732209 regulation of ligase activity 5.732209 regulation of ubiquitin-protein ligase activity 5.732209 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 5.732209 JNK cascade 5.730845 ubiquitin-dependent protein catabolic process 5.470467 negative regulation of type I interferon production 5.321883 modification-dependent macromolecule catabolic process 5.321579 modification-dependent protein catabolic process 5.321579 cellular macromolecule catabolic process 5.321522 negative regulation of protein ubiquitination 5.315509 S phase 5.314877 S phase of mitotic cell cycle 5.314877 nucleotide-binding oligomerization domain containing signaling pathway 5.314768 cellular protein catabolic process 5.295468 proteolysis involved in cellular protein catabolic process 5.295468 protein catabolic process 5.100351 regulation of I-kappaB kinase/NF-kappaB cascade 5.099621 mRNA metabolic process 5.074748 macromolecule catabolic process 5.002732 positive regulation of protein ubiquitination 4.892213 positive regulation of I-kappaB kinase/NF-kappaB cascade 4.718182 DNA repair 4.711502 stress-activated MAPK cascade 4.662002 stress-activated protein kinase signaling cascade 4.662002 protein modification by small protein conjugation or removal 4.582334 cytoplasmic pattern recognition receptor signaling pathway 4.527210 nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway 4.527210 regulation of protein ubiquitination 4.292511 viral infectious cycle 4.292221 protein polyubiquitination 4.291878 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest 4.284951 signal transduction involved in DNA damage checkpoint 4.284951 signal transduction involved in DNA integrity checkpoint 4.284951 signal transduction involved in G1/S transition checkpoint 4.284951 signal transduction involved in cell cycle checkpoint 4.284951 signal transduction involved in mitotic cell cycle G1/S checkpoint 4.284951 signal transduction involved in mitotic cell cycle G1/S transition DNA damage checkpoint 4.284951 signal transduction involved in mitotic cell cycle checkpoint 4.284951 activation of protein kinase activity 3.985313 G1 phase 3.935373 G1 phase of mitotic cell cycle 3.935373 Notch signaling pathway 3.908553 proteasomal protein catabolic process 3.907745 proteasomal ubiquitin-dependent protein catabolic process 3.907745 response to DNA damage stimulus 3.821899 protein modification by small protein conjugation 3.723788 mitotic cell cycle G1/S transition DNA damage checkpoint 3.722761 DNA damage checkpoint 3.722701 DNA integrity checkpoint 3.722701 positive regulation of cell cycle arrest 3.716227 cellular protein metabolic process 3.690126 activation of MAPK activity 3.528213 regulation of cell cycle arrest 3.405880 negative regulation of cytokine production 3.345851 cellular protein modification process 3.338340 protein modification process 3.338340 cellular catabolic process 3.276816 regulation of type I interferon production 3.260822 G1/S transition of mitotic cell cycle 3.260208 G1/S transition checkpoint 3.259809 mitotic cell cycle G1/S transition checkpoint 3.259809 positive regulation of MAP kinase activity 3.226805 antigen processing and presentation of peptide antigen 3.216222 positive regulation of intracellular protein kinase cascade 3.216222 protein targeting to membrane 3.139624 regulation of intracellular protein kinase cascade 3.139197 nuclear-transcribed mRNA catabolic process 3.138640 cell cycle checkpoint 3.137555 MAPK cascade 3.137380 positive regulation of defense response 3.137198 macromolecule modification 3.132157