negative regulation of Ras protein signal transduction 16.506470 negative regulation of small GTPase mediated signal transduction 16.506470 regulation of Ras protein signal transduction 13.939043 positive regulation of Ras GTPase activity 13.099965 regulation of small GTPase mediated signal transduction 12.343105 positive regulation of GTPase activity 12.272269 regulation of Ras GTPase activity 12.272269 regulation of nucleotide metabolic process 12.229864 regulation of purine nucleotide metabolic process 12.229864 regulation of GTP catabolic process 11.762271 regulation of GTPase activity 11.762271 regulation of nucleotide catabolic process 11.762271 regulation of purine nucleotide catabolic process 11.762271