2-oxoglutarate metabolic process 9 ATP catabolic process 1 ATP metabolic process 1 DNA damage checkpoint 1 DNA damage response, signal transduction by p53 class mediator 1 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest 1 DNA integrity checkpoint 1 DNA metabolic process 7 DNA repair 7 ERBB signaling pathway 10 G1 phase 7 G1 phase of mitotic cell cycle 7 G1/S transition checkpoint 1 G1/S transition of mitotic cell cycle 1 G2/M transition of mitotic cell cycle 1 I-kappaB kinase/NF-kappaB cascade 7 ISG15-protein conjugation 3 JNK cascade 7 M phase 1 M phase of mitotic cell cycle 1 M/G1 transition of mitotic cell cycle 1 MAPK cascade 10 MyD88-dependent toll-like receptor signaling pathway 10 MyD88-independent toll-like receptor signaling pathway 10 Notch signaling pathway 3 RNA biosynthetic process 4 RNA metabolic process 1 Ras protein signal transduction 4 S phase 1 S phase of mitotic cell cycle 1 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process 3 T cell costimulation 2 T cell receptor signaling pathway 5 TRIF-dependent toll-like receptor signaling pathway 10 Wnt receptor signaling pathway 1 acetyl-CoA catabolic process 9 acetyl-CoA metabolic process 9 activation of MAPK activity 10 activation of MAPKK activity 10 activation of innate immune response 5 activation of protein kinase activity 10 aerobic respiration 9 ameboidal cell migration 4 amine biosynthetic process 9 amine metabolic process 9 anaphase 1 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process 1 anatomical structure development 4 anatomical structure formation involved in morphogenesis 4 anatomical structure morphogenesis 4 antigen processing and presentation 1 antigen processing and presentation of exogenous antigen 1 antigen processing and presentation of exogenous peptide antigen 1 antigen processing and presentation of exogenous peptide antigen via MHC class I 1 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent 1 antigen processing and presentation of peptide antigen 1 antigen processing and presentation of peptide antigen via MHC class I 1 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II 2 apoptotic process 1 aspartate family amino acid metabolic process 9 autonomic nervous system development 4 axon guidance 10 axonogenesis 10 biological regulation 1 biosynthetic process 4 blood vessel development 4 blood vessel endothelial cell migration 4 blood vessel morphogenesis 4 branching morphogenesis of a tube 4 camera-type eye development 4 camera-type eye morphogenesis 4 carbohydrate biosynthetic process 9 carbohydrate catabolic process 9 carbohydrate derivative catabolic process 1 carbohydrate derivative metabolic process 2 carbohydrate metabolic process 9 carboxylic acid biosynthetic process 9 carboxylic acid catabolic process 9 carboxylic acid metabolic process 9 cardiovascular system development 4 catabolic process 1 catechol-containing compound biosynthetic process 2 catechol-containing compound metabolic process 2 catecholamine biosynthetic process 2 catecholamine metabolic process 2 cell aging 4 cell communication 1 cell cycle 1 cell cycle checkpoint 1 cell cycle phase 1 cell cycle process 1 cell death 1 cell development 4 cell differentiation 4 cell division 1 cell fate commitment 4 cell morphogenesis 10 cell morphogenesis involved in differentiation 10 cell morphogenesis involved in neuron differentiation 10 cell motility 4 cell part morphogenesis 10 cell projection morphogenesis 10 cell projection organization 10 cell surface receptor signaling pathway 10 cellular amine metabolic process 2 cellular amino acid biosynthetic process 9 cellular amino acid catabolic process 9 cellular amino acid metabolic process 9 cellular aromatic compound metabolic process 9 cellular biogenic amine biosynthetic process 9 cellular biogenic amine metabolic process 2 cellular biosynthetic process 4 cellular carbohydrate metabolic process 9 cellular catabolic process 1 cellular component biogenesis at cellular level 7 cellular component morphogenesis 4 cellular component organization 10 cellular component organization at cellular level 10 cellular component organization or biogenesis 10 cellular component organization or biogenesis at cellular level 10 cellular developmental process 4 cellular ketone metabolic process 9 cellular localization 2 cellular macromolecular complex assembly 10 cellular macromolecular complex subunit organization 10 cellular macromolecule biosynthetic process 4 cellular macromolecule catabolic process 1 cellular macromolecule localization 2 cellular macromolecule metabolic process 1 cellular membrane organization 1 cellular metabolic process 1 cellular modified amino acid metabolic process 9 cellular nitrogen compound biosynthetic process 9 cellular nitrogen compound catabolic process 1 cellular nitrogen compound metabolic process 1 cellular process 1 cellular process involved in reproduction 4 cellular protein catabolic process 1 cellular protein complex assembly 10 cellular protein localization 2 cellular protein metabolic process 1 cellular protein modification process 1 cellular response to chemical stimulus 4 cellular response to decreased oxygen levels 4 cellular response to fibroblast growth factor stimulus 10 cellular response to growth factor stimulus 4 cellular response to hypoxia 4 cellular response to inorganic substance 4 cellular response to insulin stimulus 10 cellular response to metal ion 4 cellular response to oxygen levels 4 cellular response to stimulus 1 cellular response to stress 1 chemotaxis 10 chondrocyte differentiation 2 chordate embryonic development 4 chromatin modification 4 chromatin organization 4 chromosome organization 4 circulatory system development 4 cochlea development 1 coenzyme catabolic process 9 coenzyme metabolic process 9 cofactor catabolic process 9 cofactor metabolic process 9 cognition 4 columnar/cuboidal epithelial cell differentiation 4 cytokinesis 10 cytoplasmic pattern recognition receptor signaling pathway 7 cytoplasmic sequestering of protein 5 cytoplasmic sequestering of transcription factor 5 death 1 development of primary male sexual characteristics 4 development of primary sexual characteristics 4 developmental pigmentation 4 developmental process 4 developmental process involved in reproduction 4 dicarboxylic acid metabolic process 9 digestive system development 4 digestive tract development 4 digestive tract morphogenesis 2 diol biosynthetic process 2 diol metabolic process 2 embryo development 4 embryo development ending in birth or egg hatching 4 embryonic digestive tract development 5 embryonic morphogenesis 4 embryonic organ development 4 embryonic placenta development 4 endosomal transport 7 enzyme linked receptor protein signaling pathway 10 epidermal growth factor receptor signaling pathway 10 epithelial cell differentiation 4 epithelial to mesenchymal transition 4 epithelial tube morphogenesis 4 epithelium development 4 establishment of organelle localization 1 establishment of protein localization 2 exocytosis 8 eye development 4 fibroblast growth factor receptor signaling pathway 10 gene expression 4 generation of neurons 4 generation of precursor metabolites and energy 9 gland development 4 gland morphogenesis 4 gluconeogenesis 9 glucose catabolic process 9 glucose metabolic process 9 glutamate metabolic process 9 glutamine family amino acid biosynthetic process 9 glutamine family amino acid catabolic process 9 glutamine family amino acid metabolic process 9 glycerolipid biosynthetic process 10 glycerolipid metabolic process 10 glycerophospholipid biosynthetic process 10 glycerophospholipid metabolic process 10 glycolysis 9 gonad development 4 heart development 4 heart morphogenesis 4 hemopoiesis 4 hemopoietic or lymphoid organ development 4 heterocycle biosynthetic process 2 heterocycle catabolic process 1 heterocycle metabolic process 2 hexose biosynthetic process 9 hexose catabolic process 9 hexose metabolic process 9 immune system development 4 immune system process 1 in utero embryonic development 4 induction of apoptosis by extracellular signals 10 innate immune response-activating signal transduction 5 inositol lipid-mediated signaling 10 insulin receptor signaling pathway 10 interphase 1 interphase of mitotic cell cycle 1 interspecies interaction between organisms 1 intracellular protein transport 2 intracellular signal transduction 1 intracellular transport 2 kidney development 2 learning 4 learning or memory 4 lipid catabolic process 2 lipid modification 10 localization of cell 4 lymphocyte costimulation 2 mRNA metabolic process 1 macromolecule biosynthetic process 4 macromolecule catabolic process 1 macromolecule localization 2 macromolecule metabolic process 1 macromolecule modification 1 maintenance of location 8 maintenance of location in cell 5 maintenance of protein location 5 maintenance of protein location in cell 5 male gonad development 4 male sex differentiation 4 mammary gland development 4 membrane lipid biosynthetic process 7 membrane organization 1 mesenchymal cell development 4 mesenchymal cell differentiation 4 mesenchyme development 4 metabolic process 1 metanephros development 4 microtubule-based process 10 mitosis 1 mitotic cell cycle 1 mitotic cell cycle G1/S transition DNA damage checkpoint 1 mitotic cell cycle G1/S transition checkpoint 1 mitotic cell cycle checkpoint 1 mitotic cell cycle spindle assembly checkpoint 1 mitotic cell cycle spindle checkpoint 1 modification-dependent macromolecule catabolic process 1 modification-dependent protein catabolic process 1 monocarboxylic acid metabolic process 9 monosaccharide biosynthetic process 9 monosaccharide catabolic process 9 monosaccharide metabolic process 9 morphogenesis of a branching epithelium 4 morphogenesis of a branching structure 4 morphogenesis of an epithelium 4 multi-organism process 3 multicellular organismal development 4 multicellular organismal process 4 muscle cell development 2 muscle cell differentiation 4 muscle structure development 4 muscle tissue development 4 myeloid leukocyte differentiation 4 negative regulation of ERBB signaling pathway 7 negative regulation of I-kappaB kinase/NF-kappaB cascade 10 negative regulation of NF-kappaB import into nucleus 5 negative regulation of NF-kappaB transcription factor activity 5 negative regulation of RNA metabolic process 4 negative regulation of Wnt receptor signaling pathway 2 negative regulation of apoptotic process 4 negative regulation of biological process 1 negative regulation of biosynthetic process 4 negative regulation of blood coagulation 8 negative regulation of canonical Wnt receptor signaling pathway 5 negative regulation of catalytic activity 1 negative regulation of cell communication 3 negative regulation of cell cycle 1 negative regulation of cell cycle process 1 negative regulation of cell death 4 negative regulation of cell proliferation 4 negative regulation of cellular biosynthetic process 4 negative regulation of cellular component organization 1 negative regulation of cellular macromolecule biosynthetic process 4 negative regulation of cellular metabolic process 1 negative regulation of cellular process 1 negative regulation of cellular protein metabolic process 1 negative regulation of coagulation 8 negative regulation of epidermal growth factor receptor signaling pathway 7 negative regulation of gene expression 4 negative regulation of hemostasis 8 negative regulation of ligase activity 1 negative regulation of macromolecule biosynthetic process 4 negative regulation of macromolecule metabolic process 1 negative regulation of metabolic process 1 negative regulation of mitosis 1 negative regulation of mitotic metaphase/anaphase transition 1 negative regulation of molecular function 1 negative regulation of nitrogen compound metabolic process 4 negative regulation of nuclear division 1 negative regulation of nucleobase-containing compound metabolic process 4 negative regulation of nucleocytoplasmic transport 5 negative regulation of organelle organization 1 negative regulation of programmed cell death 4 negative regulation of protein import into nucleus 5 negative regulation of protein metabolic process 1 negative regulation of protein modification process 1 negative regulation of protein ubiquitination 1 negative regulation of signal transduction 3 negative regulation of signaling 3 negative regulation of transcription factor import into nucleus 5 negative regulation of transcription from RNA polymerase II promoter 4 negative regulation of transcription, DNA-dependent 4 negative regulation of transmembrane transport 5 negative regulation of type I interferon production 1 negative regulation of ubiquitin-protein ligase activity 1 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 1 nephron development 4 nerve growth factor receptor signaling pathway 10 nervous system development 4 neural crest cell development 4 neural crest cell differentiation 4 neural crest cell migration 4 neurogenesis 4 neuron differentiation 4 neuron projection development 10 neuron projection morphogenesis 10 nitrogen compound metabolic process 1 nuclear division 1 nucleic acid metabolic process 1 nucleobase-containing compound catabolic process 1 nucleobase-containing compound metabolic process 1 nucleobase-containing small molecule metabolic process 9 nucleoside monophosphate biosynthetic process 9 nucleoside phosphate metabolic process 2 nucleoside triphosphate catabolic process 1 nucleoside triphosphate metabolic process 1 nucleotide catabolic process 1 nucleotide metabolic process 2 nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway 7 nucleotide-binding oligomerization domain containing signaling pathway 7 organ development 4 organ morphogenesis 4 organelle fission 1 organelle localization 10 organelle organization 1 organic acid biosynthetic process 9 organic acid catabolic process 9 organic acid metabolic process 9 organic substance metabolic process 2 organic substance transport 2 organophosphate metabolic process 10 oxaloacetate metabolic process 9 oxidation-reduction process 9 oxoacid metabolic process 9 pattern recognition receptor signaling pathway 5 pattern specification process 4 phenol-containing compound metabolic process 9 phosphate-containing compound metabolic process 10 phosphatidylinositol 3-kinase cascade 10 phosphatidylinositol biosynthetic process 10 phosphatidylinositol metabolic process 10 phosphatidylinositol-mediated signaling 10 phospholipid biosynthetic process 10 phospholipid metabolic process 10 phosphorus metabolic process 10 phosphorylation 10 pituitary gland development 1 placenta development 4 platelet degranulation 8 positive regulation of BMP signaling pathway 4 positive regulation of DNA replication 10 positive regulation of ERBB signaling pathway 10 positive regulation of GTPase activity 10 positive regulation of I-kappaB kinase/NF-kappaB cascade 3 positive regulation of MAP kinase activity 10 positive regulation of NF-kappaB transcription factor activity 7 positive regulation of RNA metabolic process 4 positive regulation of Ras GTPase activity 10 positive regulation of Wnt receptor signaling pathway 1 positive regulation of biological process 1 positive regulation of biosynthetic process 4 positive regulation of catalytic activity 1 positive regulation of cell communication 10 positive regulation of cell cycle arrest 1 positive regulation of cell cycle process 1 positive regulation of cellular biosynthetic process 4 positive regulation of cellular metabolic process 1 positive regulation of cellular process 1 positive regulation of cellular protein metabolic process 1 positive regulation of chromosome organization 5 positive regulation of endothelial cell proliferation 4 positive regulation of epidermal growth factor receptor signaling pathway 10 positive regulation of fibroblast proliferation 4 positive regulation of gene expression 4 positive regulation of innate immune response 10 positive regulation of kinase activity 10 positive regulation of ligase activity 1 positive regulation of macromolecule biosynthetic process 4 positive regulation of macromolecule metabolic process 1 positive regulation of metabolic process 1 positive regulation of molecular function 1 positive regulation of neural precursor cell proliferation 5 positive regulation of nitrogen compound metabolic process 4 positive regulation of nucleobase-containing compound metabolic process 4 positive regulation of phosphate metabolic process 10 positive regulation of phosphorus metabolic process 10 positive regulation of phosphorylation 10 positive regulation of proteasomal ubiquitin-dependent protein catabolic process 6 positive regulation of protein catabolic process 1 positive regulation of protein kinase activity 10 positive regulation of protein metabolic process 1 positive regulation of protein modification process 1 positive regulation of protein phosphorylation 10 positive regulation of protein serine/threonine kinase activity 10 positive regulation of protein ubiquitination 1 positive regulation of proteolysis 5 positive regulation of response to stimulus 10 positive regulation of signal transduction 10 positive regulation of signaling 10 positive regulation of transcription from RNA polymerase II promoter 4 positive regulation of transcription, DNA-dependent 4 positive regulation of transferase activity 10 positive regulation of ubiquitin-protein ligase activity 1 positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 1 post-Golgi vesicle-mediated transport 2 primary metabolic process 1 programmed cell death 1 proteasomal protein catabolic process 1 proteasomal ubiquitin-dependent protein catabolic process 1 protein K11-linked ubiquitination 1 protein K48-linked ubiquitination 3 protein K63-linked ubiquitination 3 protein autophosphorylation 4 protein autoubiquitination 6 protein catabolic process 1 protein folding 7 protein localization 2 protein localization to organelle 10 protein metabolic process 1 protein modification by small protein conjugation 1 protein modification by small protein conjugation or removal 1 protein modification by small protein removal 1 protein modification process 1 protein monoubiquitination 3 protein phosphorylation 10 protein polyubiquitination 1 protein ubiquitination 1 protein ubiquitination involved in ubiquitin-dependent protein catabolic process 3 proteolysis 1 proteolysis involved in cellular protein catabolic process 1 proximal/distal pattern formation 1 purine nucleoside triphosphate catabolic process 1 purine nucleoside triphosphate metabolic process 1 purine nucleotide catabolic process 1 purine nucleotide metabolic process 2 purine ribonucleoside triphosphate catabolic process 1 purine ribonucleoside triphosphate metabolic process 1 purine ribonucleotide catabolic process 1 purine ribonucleotide metabolic process 1 purine-containing compound catabolic process 1 purine-containing compound metabolic process 2 rRNA metabolic process 7 rRNA processing 7 regulation of BMP signaling pathway 4 regulation of DNA replication 1 regulation of ERBB signaling pathway 10 regulation of G1/S transition of mitotic cell cycle 1 regulation of I-kappaB kinase/NF-kappaB cascade 7 regulation of MAP kinase activity 10 regulation of RNA biosynthetic process 4 regulation of RNA metabolic process 4 regulation of Ras GTPase activity 10 regulation of Ras protein signal transduction 10 regulation of Rho protein signal transduction 10 regulation of Wnt receptor signaling pathway 1 regulation of apoptotic process 1 regulation of biological process 1 regulation of biosynthetic process 4 regulation of canonical Wnt receptor signaling pathway 1 regulation of catabolic process 1 regulation of catalytic activity 1 regulation of cell communication 10 regulation of cell cycle 1 regulation of cell cycle arrest 1 regulation of cell cycle process 1 regulation of cell death 1 regulation of cell differentiation 4 regulation of cell proliferation 4 regulation of cellular amine metabolic process 1 regulation of cellular amino acid metabolic process 1 regulation of cellular biosynthetic process 4 regulation of cellular catabolic process 5 regulation of cellular component organization 10 regulation of cellular ketone metabolic process 1 regulation of cellular macromolecule biosynthetic process 4 regulation of cellular metabolic process 1 regulation of cellular process 1 regulation of cellular protein metabolic process 1 regulation of cyclin-dependent protein kinase activity 5 regulation of developmental process 4 regulation of endopeptidase activity 5 regulation of epidermal growth factor receptor signaling pathway 10 regulation of fibroblast proliferation 4 regulation of gene expression 4 regulation of hormone metabolic process 4 regulation of interphase of mitotic cell cycle 1 regulation of kinase activity 10 regulation of ligase activity 1 regulation of macromolecule biosynthetic process 4 regulation of macromolecule metabolic process 1 regulation of metabolic process 1 regulation of mitosis 1 regulation of mitotic cell cycle 1 regulation of mitotic metaphase/anaphase transition 1 regulation of molecular function 1 regulation of multicellular organismal development 4 regulation of multicellular organismal process 4 regulation of neurotransmitter levels 2 regulation of nitric-oxide synthase activity 10 regulation of nitrogen compound metabolic process 1 regulation of nuclear division 1 regulation of nucleobase-containing compound metabolic process 4 regulation of organelle organization 1 regulation of peptidase activity 5 regulation of phosphate metabolic process 10 regulation of phosphorus metabolic process 10 regulation of phosphorylation 10 regulation of primary metabolic process 1 regulation of programmed cell death 1 regulation of proteasomal protein catabolic process 1 regulation of proteasomal ubiquitin-dependent protein catabolic process 6 regulation of protein catabolic process 1 regulation of protein kinase activity 10 regulation of protein metabolic process 1 regulation of protein modification process 1 regulation of protein phosphorylation 10 regulation of protein serine/threonine kinase activity 10 regulation of protein tyrosine kinase activity 10 regulation of protein ubiquitination 1 regulation of proteolysis 1 regulation of signal transduction 10 regulation of signaling 10 regulation of small GTPase mediated signal transduction 10 regulation of smoothened signaling pathway 5 regulation of transcription factor import into nucleus 5 regulation of transcription from RNA polymerase II promoter 4 regulation of transcription involved in G1/S phase of mitotic cell cycle 1 regulation of transcription, DNA-dependent 4 regulation of transferase activity 10 regulation of type I interferon production 3 regulation of ubiquitin-protein ligase activity 1 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 1 renal system development 4 reproductive structure development 4 response to DNA damage stimulus 1 response to abiotic stimulus 4 response to chemical stimulus 4 response to endogenous stimulus 4 response to external stimulus 4 response to fibroblast growth factor stimulus 10 response to growth factor stimulus 4 response to purine-containing compound 9 response to stimulus 1 response to stress 1 response to toxin 2 ribonucleoprotein complex biogenesis 7 ribonucleoside monophosphate biosynthetic process 9 ribonucleoside triphosphate catabolic process 1 ribonucleoside triphosphate metabolic process 1 ribonucleotide catabolic process 1 ribonucleotide metabolic process 1 ribosome biogenesis 7 sensory organ development 4 sex differentiation 4 signal transduction 1 signal transduction by p53 class mediator 1 signal transduction in response to DNA damage 1 signal transduction involved in DNA damage checkpoint 1 signal transduction involved in DNA integrity checkpoint 1 signal transduction involved in G1/S transition checkpoint 1 signal transduction involved in cell cycle checkpoint 1 signal transduction involved in mitotic cell cycle G1/S checkpoint 1 signal transduction involved in mitotic cell cycle G1/S transition DNA damage checkpoint 1 signal transduction involved in mitotic cell cycle checkpoint 1 signaling 1 skeletal system development 4 skin development 4 small molecule biosynthetic process 9 small molecule catabolic process 9 small molecule metabolic process 1 smoothened signaling pathway 1 sphingolipid biosynthetic process 7 spindle assembly checkpoint 1 spindle checkpoint 1 sprouting angiogenesis 4 striated muscle cell development 2 striated muscle tissue development 4 sulfur compound metabolic process 9 sympathetic nervous system development 4 synaptic transmission 2 synaptic vesicle transport 2 system development 4 taxis 10 tissue development 4 tissue morphogenesis 4 toll-like receptor 1 signaling pathway 10 toll-like receptor 2 signaling pathway 10 toll-like receptor 3 signaling pathway 10 transcription from RNA polymerase II promoter 4 transcription, DNA-dependent 4 transmembrane receptor protein tyrosine kinase signaling pathway 10 tricarboxylic acid cycle 9 tube development 4 tube morphogenesis 4 ubiquitin-dependent protein catabolic process 1 ureteric bud development 4 urogenital system development 4 vasculature development 4 vesicle localization 10 vesicle-mediated transport 2 viral assembly, maturation, egress, and release 1 viral infectious cycle 1 viral reproduction 1 viral reproductive process 1